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PLoS One ; 15(7): e0236860, 2020.
Article in English | MEDLINE | ID: covidwho-690729

ABSTRACT

Currently, novel coronavirus disease 2019 (COVID-19) is a big threat to global health. The rapid spread of the virus has created pandemic, and countries all over the world are struggling with a surge in COVID-19 infected cases. There are no drugs or other therapeutics approved by the US Food and Drug Administration to prevent or treat COVID-19: information on the disease is very limited and scattered even if it exists. This motivates the use of data integration, combining data from diverse sources and eliciting useful information with a unified view of them. In this paper, we propose a Bayesian hierarchical model that integrates global data for real-time prediction of infection trajectory for multiple countries. Because the proposed model takes advantage of borrowing information across multiple countries, it outperforms an existing individual country-based model. As fully Bayesian way has been adopted, the model provides a powerful predictive tool endowed with uncertainty quantification. Additionally, a joint variable selection technique has been integrated into the proposed modeling scheme, which aimed to identify possible country-level risk factors for severe disease due to COVID-19.


Subject(s)
Betacoronavirus , Coronavirus Infections/epidemiology , Coronavirus Infections/transmission , Global Health/trends , Pneumonia, Viral/epidemiology , Pneumonia, Viral/transmission , Bayes Theorem , COVID-19 , Coronavirus Infections/virology , Humans , Models, Theoretical , Pandemics , Pneumonia, Viral/virology , Prognosis , Risk Factors , SARS-CoV-2 , Travel , Uncertainty
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